'These findings demand a reexamination of transplant using organs from patients with brain cancer,' Fong added. The 10-year survival of transplants from donors with brain cancer was 65% for single kidney transplants, 69% for liver transplants, 73% for heart transplants, and 46% for lung transplants.ĭespite a push to increase the donor pool for those awaiting transplants, 'malignancy has been a relative contraindication for donors to be considered for organ transplant because of data showing poor outcomes from an era when organs from deceased patients with cancer were commonly used and when staging for cancer by imaging was poor,' wrote Yuman Fong, MD, of the City of Hope Medical Center in Duarte, California, in an invited commentary. They also noted that while active cancers usually prevent organ donation, organs from patients with primary brain tumors are generally more accepted because these cancers rarely spread beyond the central nervous system, lowering the risk of cancer transmission.

'Results suggest that donors with brain tumors were a source of good-quality organs, as evidenced by favorable risk markers and excellent transplant outcomes.' 'No transmissions occurred despite many donors having high-grade tumors or undergoing prior surgical intervention, both of which are considered as increasing the risk of transmission,' Greenhall and colleagues wrote. = != !=!=:=/= & & &= ++ +++ *** !! ?: ?.Compared with matched controls who received transplants from donors without brain tumors, transplant survival was equivalent, though kidney, liver, and lung utilization were lower in donors with high-grade brain tumors, they noted in JAMA Surgery.

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